Cell Line Lysates
Cayman Chemical AvermectIn B1b 2.5mg
An antibiotic active against Gram-positive bacteria including resistant species (MICs 2-4 mg/ml) inhibits protein synthesis by binding to domain V of the 23S ribosomal RNA of the 50S subunit of bacterial ribosomes reduces pulmonary MRSA load in spontaneously breathing and mechanically ventilated rabbits at 50 mg/kg
Cayman Chemical OlIgomycIn D 2.5mg
An irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis displays antiangiogenic cytostatic and antiparasitic effects
Cayman Chemical LPSSchRIchIa colI O55 2.5mg
Specificity MouseExcitation max 565540498 nmEmission max 578 nmUses Flow cytometry Fluorescence microscopy
Cayman Chemical E6 BerbamIn 10mg
A non-peptide inhibitor of BACE1 (IC50 239 nM) that demonstrates 10-fold selectivity over BACE2 and 50-fold selectivity over other aspartyl proteases decreases AB in APP-overexpressing cells and transgenic animal models and reduces C99 and sAPPB the two primary APP cleavage products generated by BACE1
Cell Signaling Technology PathScanR Phospho-MLKL Ser345 Chemiluminescent Sandwich ELISA Kit 5 Kit
PathScanR Phospho-MLKL Ser345 Chemiluminescent Sandwich ELISA Kit 5 Kit
Cell Signaling Technology PathScanR Phospho-MLKL Ser358 Chemiluminescent Sandwich ELISA Kit 10 Kit
PathScanR Phospho-MLKL Ser358 Chemiluminescent Sandwich ELISA Kit 10 Kit
Cell Signaling Technology PathScanR Total MUC1 Sandwich ELISA Kit 5 Kit
PathScanR Total MUC1 Sandwich ELISA Kit 5 Kit
Cell Signaling Technology Glucocorticoid Receptor D6H2L XPRRabbit mAb InTraSeqtm 3 Conjugate 3035 25 ul
Glucocorticoid Receptor D6H2L XPRRabbit mAb InTraSeqtm 3 Conjugate 3035 25 ul
Cayman Chemical Scopulaops F244 ymglusn 2.5mg
A potent ghrelin receptor antagonist (IC50 1 1 nM) that inhibits hexarelin-stimulated food intake by as much as 98 in rats at 80 Ug/kg does not affect growth hormone release when tested in infant rats
Cayman Chemical ChaetomInIn 2.5mg
20-carboxy Arachdonc acd (20-COOH-AA) s the major metabolte of 20-HETE that s produced n renal tubular epthelal endothelal and mcrovascular smooth muscle cell cultures Ths -oxdaton converson can take place usng purfed alcohol dehydrogenases three and four or by mcrosomes contanng recombnant human CYP4F3B 14780 Lke 20-HETE 20-COOH-AA nhbts on transport n the kdneys t also produces vasorelaxaton of porcne coronary mcrovessels constrcted wth endotheln 20-COOH-AA bnds to solated lgand bndng domans of peroxsome prolferator-actvated receptor a (PPARa) (Kd 0 87 0 12 UM) and PPARY (Kd 1 7 0 5 UM) and s a dual actvator of PPARa and PPARY n a transently transfected COS-7 cell reporter system 14780
Cayman Chemical A-54556B 2.5mg
A natural product which acts as a small molecule inhibitor of HIF signaling disrupting the binding of HIF-1a and HIF-2a to p300 at low nanomolar concentrations effectively attenuates the HIF pathway both in cells and in vivo in mice
Cayman Chemical MIcrococcIn P1 2.5mg
A class III antiarrhythmic agent inhibits IKr in AT-1 myocytes (IC50 20 nM) enhances INa and increases the action potential duration in isolated guinea pig ventricular cells decreases pinacidil-induced ventricular fibrillation in Langendorff isolated perfused rabbit hearts from 3-30 UM increases the ERP of the left and right atrium in anesthetized pigs at 15 Ug/kg i.v. prevents rapid pacing-induced atrial flutter in dogs from 0.25-5 mg/kg
Cayman Chemical EpIbenzomalvIn E 2.5mg
An antiparasitic agent induces swelling and blebbing and reduces motility of F. hepatica mature flukes at 10 Ug/ml reduces the number of flukes in a goat model of F. hepatica infection from 3.5-15 mg/kg completely eradicates naturally acquired F. hepatica adult flukes in sheep and cattle at 7 mg/kg